K-Ras Polyclonal Antibody
Rabbit Anti-K-Ras Polyclonal Antibody
Product Specifications
Background
KRAS (KRAS proto-oncogene, GTPase), a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
CAS Number
9007-83-4
Gene ID
3845
Accession Number
P01116
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the C-ternal region of human KRAS
Clonality
Polyclonal
Tag
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
22kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
K-Ras Polyclonal Antibody detects endogenous levels of v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
Observed Molecular Weight
22
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 100-300; WB 1:500-1:2000; ELISA 1:10000; IF 1:50-200
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P01116
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1213886-01 0.02 mg (E-Coli)
Recombinant Streptococcus sanguinis CCA-adding enzyme (cca)
Sign In for Pricing
View Details MBS1213886-02 0.02 mg (Yeast)
Recombinant Streptococcus sanguinis CCA-adding enzyme (cca)
Sign In for Pricing
View Details MBS1213886-03 0.1 mg (E-Coli)
Recombinant Streptococcus sanguinis CCA-adding enzyme (cca)
Sign In for Pricing
View Details MBS1213886-04 0.1 mg (Yeast)
Recombinant Streptococcus sanguinis CCA-adding enzyme (cca)
Sign In for Pricing
View Details MBS1213886-05 0.02 mg (Baculovirus)
Recombinant Streptococcus sanguinis CCA-adding enzyme (cca)
Sign In for Pricing
View Details