RNase III Drosha Polyclonal Antibody

Rabbit Anti-RNase III Drosha Polyclonal Antibody

Product Specifications

Background

Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al. 2002 [PubMed 12191433]) . The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al. 2003 [PubMed 14508493]) .

CAS Number

9007-83-4

Product Name Alternative

DROSHA; RN3; RNASE3L; RNASEN; Ribonuclease 3; Protein Drosha; Ribonuclease III; RNase III; p241

Gene ID

29102

Accession Number

Q9NRR4

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human RNase III Drosha

Clonality

Polyclonal

Tag

Ribonuclease 3

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

160kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

RNase III Drosha Polyclonal Antibody detects endogenous levels of RNase III Drosha protein.

Observed Molecular Weight

160

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:10000; IF 1:50-200

Other Product Names

DROSHA; RN3; RNASE3L; RNASEN; Ribonuclease 3; Protein Drosha; Ribonuclease III; RNase III; p241

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q9NRR4

Isotype

Rabbit IgG

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS1226347-01 0.02 mg (E-Coli)

Recombinant Halobacterium salinarum Probable 6-carboxy-5,6,7,8-tetrahydropterin synthase (queD)

Ask

View Details

MBS1226347-02 0.1 mg (E-Coli)

Recombinant Halobacterium salinarum Probable 6-carboxy-5,6,7,8-tetrahydropterin synthase (queD)

Ask

View Details

MBS1226347-03 0.02 mg (Yeast)

Recombinant Halobacterium salinarum Probable 6-carboxy-5,6,7,8-tetrahydropterin synthase (queD)

Ask

View Details

MBS1226347-04 0.1 mg (Yeast)

Recombinant Halobacterium salinarum Probable 6-carboxy-5,6,7,8-tetrahydropterin synthase (queD)

Ask

View Details

MBS1226347-05 0.02 mg (Baculovirus)

Recombinant Halobacterium salinarum Probable 6-carboxy-5,6,7,8-tetrahydropterin synthase (queD)

Ask

View Details

MBS1226347-06 0.02 mg (Mammalian-Cell)

Recombinant Halobacterium salinarum Probable 6-carboxy-5,6,7,8-tetrahydropterin synthase (queD)

Ask

View Details