MI-1904
MI-1904 is the inhibitor for matriptase/TMPRSS2, that exhibits antiviral activity against influenza virus H1N1 and H9N2. MI-1904 blocks the cleavage of glycoproteins on the viral surface, prevents the virus from binding to host cell receptors, and thus inhibits the entry and replication of the virus[1].
Product Specifications
CAS Number
3033379-90-4
UNSPSC
12352005
Target
Influenza Virus; SARS-CoV; Ser/Thr Protease
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mi-1904.html
Smiles
O=S(C1=CC=CC(C2=CC=C(CO)C(F)=C2)=C1)(N[C@@H](CC3=CC(C(N)=N)=CC=C3)C(N4CCC(NC(NC(C)(C)C)=O)CC4)=O)=O
Molecular Formula
C33H41FN6O5S
Molecular Weight
652.78
References & Citations
[1]Gamba D, et al., PK/PD investigation of antiviral host matriptase/TMPRSS2 inhibitors in cell models. Sci Rep. 2024 Jul 18;14 (1) :16621.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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