Dyrk1B Polyclonal Antibody

Rabbit Anti-Dyrk1B Polyclonal Antibody

Product Specifications

Background

DYRK1B (dual specificity tyrosine phosphorylation regulated kinase 1B) encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of DYRK1B may be altered in tumor cells, and mutations in DYRK1B were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

DYRK1B; MIRK; Dual specificity tyrosine-phosphorylation-regulated kinase 1B; Minibrain-related kinase; Mirk protein kinase

Gene ID

9149

Accession Number

Q9Y463

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human Dyrk1B at AA range: 300-380

Clonality

Polyclonal

Tag

Dual specificity tyrosine-phosphorylation-regulated kinase 1B

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

70kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Dyrk1B Polyclonal Antibody detects endogenous levels of Dyrk1B protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200