KLF7 Polyclonal Antibody

Rabbit Anti-KLF7 Polyclonal Antibody

Product Specifications

Background

The protein encoded by KLF7 (Kruppel like factor 7) is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of KLF7 is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

KLF7; UKLF; Krueppel-like factor 7; Ubiquitous krueppel-like factor

Gene ID

8609

Accession Number

O75840

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human KLF7 at AA range: 150-230

Clonality

Polyclonal

Tag

Krueppel-like factor 7

Applications

WB, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

41kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

KLF7 Polyclonal Antibody detects endogenous levels of KLF7 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300