RECK Polyclonal Antibody

Rabbit Anti-RECK Polyclonal Antibody

Product Specifications

Background

The protein encoded by RECK (reversion inducing cysteine rich protein with kazal motifs) is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for RECK.

CAS Number

9007-83-4

Product Name Alternative

RECK; ST15; Reversion-inducing cysteine-rich protein with Kazal motifs; hRECK; Suppressor of tumorigenicity 15 protein

Gene ID

8434

Accession Number

O95980

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the N-terminal region of human RECK at AA range: 40-120

Clonality

Polyclonal

Tag

Reversion-inducing cysteine-rich protein with Kazal motifs

Applications

IHC, IF, WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

110kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

RECK Polyclonal Antibody detects endogenous levels of RECK protein.

Observed Molecular Weight

110

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.