ATRIP (phospho Ser68) Polyclonal Antibody

Rabbit Anti-ATRIP (phospho Ser68) Polyclonal Antibody

Product Specifications

Background

ATRIP (ATR interacting protein) encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.

CAS Number

9007-83-4

Product Name Alternative

ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein

Gene ID

84126

Accession Number

Q8WXE1

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human ATRIP around the phosphorylation site of S68

Clonality

Polyclonal

Tag

ATR-interacting protein

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

80kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-ATRIP (S68) Polyclonal Antibody detects endogenous levels of ATRIP protein only when phosphorylated at S68.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.