ZP2 Polyclonal Antibody

Rabbit Anti-ZP2 Polyclonal Antibody

Product Specifications

Background

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed of three glycoproteins with various functions during fertilization and preimplantation development. The glycosylated mature peptide is one of the structural components of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. Female mice lacking ZP2 (zona pellucida glycoprotein 2) do not form a stable zona matrix and are sterile. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

ZP2; ZPA; Zona pellucida sperm-binding protein 2; Zona pellucida glycoprotein 2; Zp-2; Zona pellucida protein A

Gene ID

7783

Accession Number

Q05996

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human ZP2

Clonality

Polyclonal

Tag

Zona pellucida sperm-binding protein 2

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

ZP2 Polyclonal Antibody detects endogenous levels of ZP2 protein.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200