ZnT-4 Polyclonal Antibody

Rabbit Anti-ZnT-4 Polyclonal Antibody

Product Specifications

Background

Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g. MIM 114852), alkaline phosphatases (e.g. MIM 171760), various dehydrogenases, and superoxide dismutases (e.g. MIM 147450) . SLC30A4 (solute carrier family 30 member 4), or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop.

CAS Number

9007-83-4

Product Name Alternative

SLC30A4; ZNT4; Zinc transporter 4; ZnT-4; Solute carrier family 30 member 4

Gene ID

7782

Accession Number

O14863

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human ZnT-4 at AA range: 40-120

Clonality

Polyclonal

Tag

Zinc transporter 4

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

47kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

ZnT-4 Polyclonal Antibody detects endogenous levels of ZnT-4 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200