V-ATPase-IN-1
V-ATPase-IN-1 (Compound 3b-03) is a Vacuolar-type H+-ATPases (V-ATPase) inhibitor (IC50 = 194.80 μM) that can effectively target the V-ATPase subunit A (Kd = 0.803 μM) . V-ATPase-IN-1 exhibits insecticidal activity against M. separata (LC50 = 2.64 mM) and contributes to research in the development of chemical insecticides[1].
Product Specifications
CAS Number
[1243603-61-3]
UNSPSC
12352101
Target
Proton Pump
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/v-atpase-in-1.html
Purity
99.23
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
ClC1=CC(CNC2=CC=CC=C2)=CC(OC)=C1OCC3=CC=CC=C3
Molecular Formula
C21H20ClNO2
Molecular Weight
353.84
References & Citations
[1]Lv B, et al. Discovery of the Chlorinated and Ammoniated Derivatives of Vanillin as Potential Insecticidal Candidates Targeting V-ATPase: Structure-Based Virtual Screening, Synthesis, and Bioassay[J]. Journal of Agricultural and Food Chemistry, 2024.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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