Linagliptin methyldimer

Linagliptin methyldimer is an impurity of Linagliptin. Linagliptin is a DPP-IV inhibitor, with IC50 of 1 nM[1].

Product Specifications

CAS Number

[1418133-47-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Dipeptidyl Peptidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/linagliptin-methyldimer.html

Purity

96.12

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(N(C1=C(C2=O)N(C(N3C[C@@H](CCC3)N)=N1)CC#CC)C)N2CC4=NC(CC5(N=C(NC6=C5C=CC=C6)CN7C(N(C8=C(C7=O)N(C(N9C[C@@H](CCC9)N)=N8)CC#CC)C)=O)C)=C%10C=CC=CC%10=N4

Molecular Formula

C50H56N16O4

Molecular Weight

945.08

Precautions

H302, H315, H319, H335

References & Citations

[1]Pfrengle, et al. Substituted quinazolines, the preparation thereof and the use thereof in pharmaceutical compositions as DPP-IV inhibitors. Patent. WO2013010964 A1.