VAMP-1/2/3 Polyclonal Antibody

Rabbit Anti-VAMP-1/2/3 Polyclonal Antibody

Product Specifications

Background

Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by VAMP1 (vesicle associated membrane protein 1) is a member of the vesicle-associated membrane protein (VAMP) /synaptobrevin family. Mutations in VAMP1 are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined.

CAS Number

9007-83-4

Product Name Alternative

VAMP1; SYB1; Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1; VAMP2; SYB2; Vesicle-associated membrane protein 2; VAMP-2; Synaptobrevin-2; VAMP3; SYB3; Vesicle-associated membrane protein 3; VAMP-3; Cellubrevin; CEB; Synaptob

Gene ID

6843/6844/9341

Accession Number

P23763/P63027/Q15836

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human VAMP-1/2/3

Clonality

Polyclonal

Tag

Vesicle-associated membrane protein 1

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

13kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

VAMP-1/2/3 Polyclonal Antibody detects endogenous levels of VAMP-1/2/3 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200