Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

BRCA2 Polyclonal Antibody

Rabbit Anti-BRCA2 Polyclonal Antibody

Product Specifications

Background

Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.

CAS Number

9007-83-4

Product Name Alternative

BRCA2; FACD; FANCD1; Breast cancer type 2 susceptibility protein; Fanconi anemia group D1 protein

Gene ID

675

Accession Number

P51587

Reactivity

Human, Rat

Immunogen

Synthesized peptide derived from the N-terminal region of human BRCA2 at AA range: 1-80

Clonality

Polyclonal

Tag

Breast cancer type 2 susceptibility protein

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

BRCA2 Polyclonal Antibody detects endogenous levels of BRCA2 protein.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200

Other Product Names

BRCA2; FACD; FANCD1; Breast cancer type 2 susceptibility protein; Fanconi anemia group D1 protein

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P51587

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rabbit Anti-NUF2 Recombinant Antibody (clone 8B7)
VS4-CJ63 Each

Rabbit Anti-NUF2 Recombinant Antibody (clone 8B7)

Sign In for Pricing
View Details
FAM187B Antibody; HRP conjugated
MBS7001327-01 0.05 mg

FAM187B Antibody; HRP conjugated

Sign In for Pricing
View Details
FAM187B Antibody; HRP conjugated
MBS7001327-02 0.1 mg

FAM187B Antibody; HRP conjugated

Sign In for Pricing
View Details
FAM187B Antibody; HRP conjugated
MBS7001327-03 5x 0.1 mg

FAM187B Antibody; HRP conjugated

Sign In for Pricing
View Details
NIPAL3 Human siRNA Oligo Duplex (Locus ID 57185)
SR311410 1 Kit

NIPAL3 Human siRNA Oligo Duplex (Locus ID 57185)

Sign In for Pricing
View Details
Serpin Peptidase Inhibitor, Clade C Member 1 Human Recombinant
rAP-4129 1 Each

Serpin Peptidase Inhibitor, Clade C Member 1 Human Recombinant

Sign In for Pricing
View Details