APC1 (phospho Ser688) Polyclonal Antibody

Rabbit Anti-APC1 (phospho Ser688) Polyclonal Antibody

Product Specifications

Background

ANAPC1 (anaphase promoting complex subunit 1) encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation.

CAS Number

9007-83-4

Product Name Alternative

ANAPC1; TSG24; Anaphase-promoting complex subunit 1; APC1; Cyclosome subunit 1; Mitotic checkpoint regulator; Testis-specific gene 24 protein

Gene ID

64682

Accession Number

Q9H1A4

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human APC1 around the phosphorylation site of S688

Clonality

Polyclonal

Tag

Anaphase-promoting complex subunit 1

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-APC1 (S688) Polyclonal Antibody detects endogenous levels of APC1 protein only when phosphorylated at S688.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.