GFRα-4 Polyclonal Antibody

Rabbit Anti-GFRα-4 Polyclonal Antibody

Product Specifications

Background

The protein encoded by GFRA4 (GDNF family receptor alpha 4) is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI) -linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. GFRA4 is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for GFRA4.

CAS Number

9007-83-4

Product Name Alternative

GFRA4; GDNF family receptor alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR-alpha-4; Persephin receptor

Gene ID

64096

Accession Number

Q9GZZ7

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human GFRα-4 at AA range: 110-190

Clonality

Polyclonal

Tag

GDNF family receptor alpha-4

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

30kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

GFRα-4 Polyclonal Antibody detects endogenous levels of GFRα-4 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.