Na+ CP type IVα Polyclonal Antibody

Rabbit Anti-Na+ CP type IVα Polyclonal Antibody

Product Specifications

Background

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN4A (sodium voltage-gated channel alpha subunit 4) encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in SCN4A have been linked to several myotonia and periodic paralysis disorders.

CAS Number

9007-83-4

Product Name Alternative

SCN4A; Sodium channel protein type 4 subunit alpha; SkM1; Sodium channel protein skeletal muscle subunit alpha; Sodium channel protein type IV subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.4

Gene ID

6329

Accession Number

P35499

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human Na+ CP type IVα at AA range: 400-480

Clonality

Polyclonal

Tag

Sodium channel protein type 4 subunit alpha

Applications

WB, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

200kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Na+ CP type IVα Polyclonal Antibody detects endogenous levels of Na+ CP type IVα protein.

Observed Molecular Weight

200

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300