RyR-2 (phospho Ser2808) Polyclonal Antibody
Rabbit Anti-RyR-2 (phospho Ser2808) Polyclonal Antibody
Product Specifications
Background
RYR2 (ryanodine receptor 2) encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in RYR2 are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.
CAS Number
9007-83-4
Product Name Alternative
RYR2; Ryanodine receptor 2; RYR-2; RyR2; hRYR-2; Cardiac muscle ryanodine receptor; Cardiac muscle ryanodine receptor-calcium release channel; Type 2 ryanodine receptor
Gene ID
6262
Accession Number
Q92736
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human RyR-2 around the phosphorylation site of S2808
Clonality
Polyclonal
Tag
Ryanodine receptor 2
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Phospho-RyR-2 (S2808) Polyclonal Antibody detects endogenous levels of RyR-2 protein only when phosphorylated at S2808.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
RYR2; Ryanodine receptor 2; RYR-2; RyR2; hRYR-2; Cardiac muscle ryanodine receptor; Cardiac muscle ryanodine receptor-calcium release channel; Type 2 ryanodine receptor
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q92736
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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