RBQ-3 Polyclonal Antibody

Rabbit Anti-RBQ-3 Polyclonal Antibody

Product Specifications

Background

RBBP5 (RB binding protein 5, histone lysine methyltransferase complex subunit) encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for RBBP5.

CAS Number

9007-83-4

Product Name Alternative

RBBP5; RBQ3; Retinoblastoma-binding protein 5; RBBP-5; Retinoblastoma-binding protein RBQ-3

Gene ID

5929

Accession Number

Q15291

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human RBQ-3 at AA range: 190-270

Clonality

Polyclonal

Tag

Retinoblastoma-binding protein 5

Applications

WB, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

59kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

RBQ-3 Polyclonal Antibody detects endogenous levels of RBQ-3 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300