Connexin 47 Polyclonal Antibody

Rabbit Anti-Connexin 47 Polyclonal Antibody

Product Specifications

Background

GJC2 (gap junction protein gamma 2) encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. GJC2 plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in GJC2 are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.

CAS Number

9007-83-4

Product Name Alternative

GJC2; GJA12; Gap junction gamma-2 protein; Connexin-46.6; Cx46.6; Connexin-47; Cx47; Gap junction alpha-12 protein

Gene ID

57165

Accession Number

Q5T442

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the N-terminal region of human Connexin 47 at AA range: 40-120

Clonality

Polyclonal

Tag

Gap junction gamma-2 protein

Applications

WB, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

47kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Connexin 47 Polyclonal Antibody detects endogenous levels of Connexin 47 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.