DNA-PKCS (phospho Thr2647) Polyclonal Antibody

Rabbit Anti-DNA-PKCS (phospho Thr2647) Polyclonal Antibody

Product Specifications

Background

PRKDC (protein kinase, DNA-activated, catalytic polypeptide) encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK) . It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.

CAS Number

9007-83-4

Product Name Alternative

PRKDC; HYRC; HYRC1; DNA-dependent protein kinase catalytic subunit; DNA-PK catalytic subunit; DNA-PKcs; DNPK1; p460

Gene ID

5591

Accession Number

P78527

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from human DNA-PKCS around the phosphorylation site of T2647

Clonality

Polyclonal

Tag

DNA-dependent protein kinase catalytic subunit

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-DNA-PKCS (T2647) Polyclonal Antibody detects endogenous levels of DNA-PKCS protein only when phosphorylated at T2647.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.