SLF80821178 (hydrochloride)
Product Specifications
UNSPSC Description
SLF80821178 hydrochloride is an orally active inhibitor for sphingosine-1-phosphate transporter (Spns2), that inhibits the sphingosine-1-phosphate (S1P) release in HeLa with an IC50 of 51 nM. SLF80821178 hydrochloride reduces the circulating lymphocyte without affecting plasma S1P levels in mice[1].
Target Antigen
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/slf80821178-hydrochloride.html
Smiles
O=C(N1CCNCC1)NC2=CC=C(CCCCCCCCCC)C=C2.Cl
Molecular Weight
381.98
References & Citations
[1]Foster DJ, et al., Discovery of Potent, Orally Bioavailable Sphingosine-1-Phosphate Transporter (Spns2) Inhibitors. J Med Chem. 2024 Jul 11;67(13):11273-11295.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162655A/SLF80821178-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162655A/
Clinical Information
No Development Reported
CAS Number
2764877-62-3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
RC221571L3V 200 µL
Ferredoxin Reductase (FDXR) (NM_004110) Human Tagged ORF Clone Lentiviral Particle
Ask
View Details