CDK5 Activator-binding C48 Polyclonal Antibody

Rabbit Anti-CDK5 Activator-binding C48 Polyclonal Antibody

Product Specifications

Background

CDK5RAP2 (CDK5 regulatory subunit associated protein 2) encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by CDK5RAP2 is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

CDK5RAP2; CEP215; KIAA1633; CDK5 regulatory subunit-associated protein 2; CDK5 activator-binding protein C48; Centrosome-associated protein 215

Gene ID

55755

Accession Number

Q96SN8

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the N-terminal region of human CDK5 Activator-binding C48 at AA range: 220-300

Clonality

Polyclonal

Tag

CDK5 regulatory subunit-associated protein 2

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

CDK5 Activator-binding C48 Polyclonal Antibody detects endogenous levels of CDK5 Activator-binding C48 protein.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200