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Butenoyl-PAF

Selected Variant

HY-126551-01

Size: 1 mg

Butenoyl-PAF is a phospholipid analog of platelet activating factor (PAF-like) that is generated in oxidized low-density lipoprotein (DLDR) . Butenoyl-PAF can activate cells that express human PAF receptors, such as neutrophils, monocytes, and platelets, and it stimulates an increase in intracellular calcium ion concentration[1].

Product Specifications

CAS Number

474944-25-7

UNSPSC

12352128

Hazard Statement

H225-H319

Target

Calcium Channel; LDLR; Platelet-activating Factor Receptor (PAFR)

Type

Reference compound

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/butenoyl-paf.html

Smiles

C=CCC(O[C@H](COCCCCCCCCCCCCCCCC)COP(OCC[N+](C)(C)C)([O-])=O)=O

Molecular Formula

C28H56NO7P

Molecular Weight

549.72

Precautions

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501

References & Citations

[1]G K Marathe, et al. Inflammatory platelet-activating factor-like phospholipids in oxidized low density lipoproteins are fragmented alkyl phosphatidylcholines. J Biol Chem. 1999 Oct 1;274 (40) :28395-404.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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