5-endo-BCN-pentanoic acid
Product Specifications
UNSPSC Description
5-endo-BCN-pentanoic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 5-endo-BCN-pentanoic acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-endo-bcn-pentanoic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCCCNC(OCC1C2CCC#CCCC12)=O
Molecular Weight
293.36
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140350/5-endo-BCN-pentanoic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140350/5-endo-BCN-pentanoic-acid-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2364591-80-8
Available Sizes
Curated Selection
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