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DNA pol ε A Polyclonal Antibody

Rabbit Anti-DNA pol ε A Polyclonal Antibody

Product Specifications

Background

POLE (DNA polymerase epsilon, catalytic subunit) encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.

CAS Number

9007-83-4

Product Name Alternative

POLE; POLE1; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A

Gene ID

5426

Accession Number

Q07864

Reactivity

Human, Rat

Immunogen

Synthesized peptide derived from the Internal region of human DNA pol ε A at AA range: 1230-1310

Clonality

Polyclonal

Tag

DNA polymerase epsilon catalytic subunit A

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

DNA pol ε A Polyclonal Antibody detects endogenous levels of DNA pol ε A protein.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200

Other Product Names

POLE; POLE1; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q07864

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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