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PKD2 (phospho Ser812) Polyclonal Antibody

Rabbit Anti-PKD2 (phospho Ser812) Polyclonal Antibody

Product Specifications

Background

PKD2 (polycystin 2, transient receptor potential cation channel) encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in PKD2 are associated with autosomal dominant polycystic kidney disease type 2.

Product Name Alternative

PKD2; Polycystin-2; Autosomal dominant polycystic kidney disease type II protein; Polycystic kidney disease 2 protein; Polycystwin; R48321

Gene ID

5311

Accession Number

Q13563

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human PKD2 around the phosphorylation site of S812

Clonality

Polyclonal

Tag

Polycystin-2

Applications

WB, ELISA, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-PKD2 (S812) Polyclonal Antibody detects endogenous levels of PKD2S812.

Product Datasheet

https://www.abbkine.com/datasheet/ABP55598.pdf

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000

Other Product Names

PKD2; Polycystin-2; Autosomal dominant polycystic kidney disease type II protein; Polycystic kidney disease 2 protein; Polycystwin; R48321

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q13563

CAS Number

9007-83-4

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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