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Sar1B Polyclonal Antibody

Rabbit Anti-Sar1B Polyclonal Antibody

Product Specifications

Background

The protein encoded by SAR1B (secretion associated Ras related GTPase 1B) is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in SAR1B are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD) . Two transcript variants encoding the same protein have been found for this gene.

CAS Number

9007-83-4

Product Name Alternative

SAR1B; SARA2; SARB; GTP-binding protein SAR1b; GTP-binding protein B; GTBPB

Gene ID

51128

Accession Number

Q9Y6B6

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human Sar1B at AA range: 80-160

Clonality

Polyclonal

Tag

GTP-binding protein SAR1b

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

22kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Sar1B Polyclonal Antibody detects endogenous levels of Sar1B protein.

Observed Molecular Weight

22

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200

Other Product Names

SAR1B; SARA2; SARB; GTP-binding protein SAR1b; GTP-binding protein B; GTBPB

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q9Y6B6

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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