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MEL-1A-R Polyclonal Antibody

Rabbit Anti-MEL-1A-R Polyclonal Antibody

Product Specifications

Background

MTNR1A encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

CAS Number

9007-83-4

Product Name Alternative

MTNR1A; Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor

Gene ID

4543

Accession Number

P48039

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human MEL-1A-R at AA range: 160-240

Clonality

Polyclonal

Tag

Melatonin receptor type 1A

Applications

WB, ELISA, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

MEL-1A-R Polyclonal Antibody detects endogenous levels of MEL-1A-R protein.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000

Other Product Names

MTNR1A; Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P48039

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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