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GCN2 (phospho Thr899) Polyclonal Antibody

Rabbit Anti-GCN2 (phospho Thr899) Polyclonal Antibody

Product Specifications

Background

EIF2AK4 encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the down regulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.

CAS Number

9007-83-4

Product Name Alternative

EIF2AK4; GCN2; KIAA1338; Eukaryotic translation initiation factor 2-alpha kinase 4; GCN2-like protein

Gene ID

440275

Accession Number

Q9P2K8

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human GCN2 around the phosphorylation site of T899

Clonality

Polyclonal

Tag

Eukaryotic translation initiation factor 2-alpha kinase 4

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-GCN2 (T899) Polyclonal Antibody detects endogenous levels of GCN2 protein only when phosphorylated at T899.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200

Other Product Names

EIF2AK4; GCN2; KIAA1338; Eukaryotic translation initiation factor 2-alpha kinase 4; GCN2-like protein

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q9P2K8

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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