3-Azidopropylamine

3-Azidopropylamine is a click chemistry reagent containing an azide group. 3-Azidopropylamine can react with the starch sugar of potato starch for complexation and transfection of plasmid DNA[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[88192-19-2]

UNSPSC

12352211

Hazard Statement

H226, H301

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/3-azidopropylamine.html

Purity

99.57

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

[N-]=[N+]=NCCCN

Molecular Formula

C3H8N4

Molecular Weight

100.12

Precautions

H226, H301

References & Citations

[1]Mai K, et, al. Cationic dendronization of amylose via click chemistry for complexation and transfection of plasmid DNA. Int J Biol Macromol. 2015 Aug;79:209-16.