MEF-2C (phospho Ser387) Polyclonal Antibody

Rabbit Anti-MEF-2C (phospho Ser387) Polyclonal Antibody

Product Specifications

Background

MEF2C encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.

CAS Number

9007-83-4

Product Name Alternative

MEF2C; Myocyte-specific enhancer factor 2C

Gene ID

4208

Accession Number

Q06413

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human MEF-2C around the phosphorylation site of S387

Clonality

Polyclonal

Tag

Myocyte-specific enhancer factor 2C

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-MEF-2C (S387) Polyclonal Antibody detects endogenous levels of MEF-2C protein only when phosphorylated at S387.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200