Arginase I Polyclonal Antibody
Rabbit Anti-Arginase I Polyclonal Antibody
Product Specifications
Background
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by ARG1, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Product Name Alternative
ARG1; Arginase-1; Liver-type arginase; Type I arginase
Gene ID
383
Accession Number
P05089
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human Arginase I at AA rangle: 30-110
Clonality
Polyclonal
Tag
Arginase-1
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
35kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Arginase I Polyclonal Antibody detects endogenous levels of Arginase I protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 100-300; WB 1:500-1:2000; ELISA 1:5000; IF 1:50-200
Other Product Names
ARG1; Arginase-1; Liver-type arginase; Type I arginase
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P05089
Isotype
Rabbit IgG
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