FAM111B Polyclonal Antibody
Rabbit Anti-FAM111B Polyclonal Antibody
Product Specifications
Background
FAM111B encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP) . Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin-like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.
CAS Number
9007-83-4
Product Name Alternative
FAM111B; CANP; Protein FAM111B; Cancer-associated nucleoprotein
Gene ID
374393
Accession Number
Q6SJ93
Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of human FAM111B at AA rangle: 250-330
Clonality
Polyclonal
Tag
Protein FAM111B
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
FAM111B Polyclonal Antibody detects endogenous levels of FAM111B protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:200; ELISA 1:5000; IF 1:50-200
Other Product Names
FAM111B; CANP; Protein FAM111B; Cancer-associated nucleoprotein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q6SJ93
Isotype
Rabbit IgG
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