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IP3R-I (phospho Ser1764) Polyclonal Antibody

Rabbit Anti-IP3R-I (phospho Ser1764) Polyclonal Antibody

Product Specifications

Background

ITPR1 encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

CAS Number

9007-83-4

Product Name Alternative

ITPR1; INSP3R1; Inositol 1; 4,5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; InsP3R1; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptor

Gene ID

3708

Accession Number

Q14643

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human IP3R-I around the phosphorylation site of S1764

Clonality

Polyclonal

Tag

Inositol 1,4,5-trisphosphate receptor type 1

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-IP3R-I (S1764) Polyclonal Antibody detects endogenous levels of IP3R-I protein only when phosphorylated at S1764.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200

Other Product Names

ITPR1; INSP3R1; Inositol 1; 4,5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; InsP3R1; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptor

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q14643

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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