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IRF-3 (phospho Ser396) Polyclonal Antibody

Rabbit Anti-IRF-3 (phospho Ser396) Polyclonal Antibody

Product Specifications

Background

IRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

CAS Number

9007-83-4

Product Name Alternative

IRF3; Interferon regulatory factor 3; IRF-3

Gene ID

3661

Accession Number

Q14653

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human IRF-3 around the phosphorylation site of S396

Clonality

Polyclonal

Tag

Interferon regulatory factor 3

Applications

WB, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

48-55kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-IRF-3 (S396) Polyclonal Antibody detects endogenous levels of IRF-3 protein only when phosphorylated at S396.

Product Datasheet

https://www.abbkine.com/datasheet/ABP54922.pdf

Observed Molecular Weight

60

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300

Other Product Names

IRF3; Interferon regulatory factor 3; IRF-3

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q14653

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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