ApoE Polyclonal Antibody
Rabbit Anti-ApoE Polyclonal Antibody
Product Specifications
Background
The protein encoded by APOE is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
CAS Number
9007-83-4
Product Name Alternative
APOE; Apolipoprotein E; Apo-E
Gene ID
348
Accession Number
P02649
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human ApoE
Clonality
Polyclonal
Tag
Apolipoprotein E
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
36kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
ApoE Polyclonal Antibody detects endogenous levels of ApoE protein.
Product Datasheet
https://www.abbkine.com/datasheet/ABP54848.pdf
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Other Product Names
APOE; Apolipoprotein E; Apo-E
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P02649
Isotype
Rabbit IgG
Available Sizes
Curated Selection
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