NMDAε4 Polyclonal Antibody

Rabbit Anti-NMDAε4 Polyclonal Antibody

Product Specifications

Background

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: nMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D) .

CAS Number

9007-83-4

Product Name Alternative

GRIN2D; GluN2D; NMDAR2D; Glutamate [NMDA] receptor subunit epsilon-4; EB11; N-methyl D-aspartate receptor subtype 2D; NMDAR2D; NR2D

Gene ID

2906

Accession Number

O15399

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Synthesized peptide derived from the Internal region of human NMDAε4 at AA rangle: 640-720

Clonality

Polyclonal

Tag

Glutamate [NMDA] receptor subunit epsilon-4

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

170kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

NMDAε4 Polyclonal Antibody detects endogenous levels of NMDAε4 protein.

Observed Molecular Weight

170

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.