Ksr2 Polyclonal Antibody

Rabbit Anti-Ksr2 Polyclonal Antibody

Product Specifications

Background

Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

CAS Number

9007-83-4

Product Name Alternative

KSR2; Kinase suppressor of Ras 2; hKSR2

Gene ID

283455

Accession Number

Q6VAB6

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human Ksr2 at AA rangle: 640-720

Clonality

Polyclonal

Tag

Kinase suppressor of Ras 2

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

108kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Ksr2 Polyclonal Antibody detects endogenous levels of Ksr2 protein.

Observed Molecular Weight

108

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.