Dkk-3 Polyclonal Antibody

Rabbit Anti-Dkk-3 Polyclonal Antibody

Product Specifications

Background

DKK3 encodes dickkopf WNT signaling pathway inhibitor 3 that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of DKK3 is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.

CAS Number

9007-83-4

Product Name Alternative

DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3

Gene ID

27122

Accession Number

Q9UBP4

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160

Clonality

Polyclonal

Tag

Dickkopf-related protein 3

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

45kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Dkk-3 Polyclonal Antibody detects endogenous levels of Dkk-3 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.