GDF-8 Polyclonal Antibody
Rabbit Anti-GDF-8 Polyclonal Antibody
Product Specifications
Background
MSTN encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.
CAS Number
9007-83-4
Product Name Alternative
MSTN; GDF8; Growth/differentiation factor 8; GDF-8; Myostatin
Gene ID
2660
Accession Number
O14793
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human GDF-8
Clonality
Polyclonal
Tag
Growth
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
GDF-8 Polyclonal Antibody detects endogenous levels of GDF-8 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
MSTN; GDF8; Growth/differentiation factor 8; GDF-8; Myostatin
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O14793
Isotype
Rabbit IgG
Available Sizes
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