GATA-4 (phospho Ser262) Polyclonal Antibody

Rabbit Anti-GATA-4 (phospho Ser262) Polyclonal Antibody

Product Specifications

Background

GATA4 encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

GATA4; Transcription factor GATA-4; GATA-binding factor 4

Gene ID

2626

Accession Number

P43694

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human GATA-4 around the phosphorylation site of S262

Clonality

Polyclonal

Tag

Transcription factor GATA-4

Applications

WB, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

48kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-GATA-4 (S262) Polyclonal Antibody detects endogenous levels of GATA-4 protein only when phosphorylated at S262.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.