Nephrocystin-4 Polyclonal Antibody
Rabbit Anti-Nephrocystin-4 Polyclonal Antibody
Product Specifications
Background
NPHP4 encodes a protein involved in renal tubular development and function. Nephrocystin-4 interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Product Name Alternative
NPHP4; KIAA0673; Nephrocystin-4; Nephroretinin
Gene ID
261734
Accession Number
O75161
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human Nephrocystin-4 at AA rangle: 850-930
Clonality
Polyclonal
Tag
Nephrocystin-4
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Nephrocystin-4 Polyclonal Antibody detects endogenous levels of Nephrocystin-4 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
NPHP4; KIAA0673; Nephrocystin-4; Nephroretinin
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O75161
Isotype
Rabbit IgG
Available Sizes
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