IFIT-5 Polyclonal Antibody

IFIT5 (Interferon Induced Protein With Tetratricopeptide Repeats 5) is a Protein Coding gene. GO annotations related to this gene include poly (A) RNA binding and tRNA binding. An important paralog of this gene is IFIT1. nterferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2-O-methylation of the 5 cap and bear a 5-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.

IFIT5; ISG58; RI58; Interferon-induced protein with tetratricopeptide repeats 5; IFIT-5; Interferon-induced 58 kDa protein; Retinoic acid- and interferon-inducible 58 kDa protein; P58

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.

IFIT5; ISG58; RI58; Interferon-induced protein with tetratricopeptide repeats 5; IFIT-5; Interferon-induced 58 kDa protein; Retinoic acid- and interferon-inducible 58 kDa protein; P58