NHE-8 Polyclonal Antibody

Rabbit Anti-NHE-8 Polyclonal Antibody

Product Specifications

Background

Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation, and electroneutral NaCl absorption in epithelia (Xu et al. 2008 [PubMed 18209477]) .

CAS Number

9007-83-4

Product Name Alternative

SLC9A8; KIAA0939; NHE8; Sodium/hydrogen exchanger 8; Na (+) /H (+) exchanger 8; NHE-8; Solute carrier family 9 member 8

Gene ID

23315

Accession Number

Q9Y2E8

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the C-terminal region of human NHE-8 at AA rangle: 420-500

Clonality

Polyclonal

Tag

Sodium hydrogen exchanger 8

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

65kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

NHE-8 Polyclonal Antibody detects endogenous levels of NHE-8 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC:1:50-300; ELISA 1:20000; IF 1:50-200