Ets-1 (phospho Ser251) Polyclonal Antibody

Rabbit Anti-Ets-1 (phospho Ser251) Polyclonal Antibody

Product Specifications

Background

ETS1 encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

CAS Number

9007-83-4

Product Name Alternative

ETS1; EWSR2; Protein C-ets-1; p54

Gene ID

2113

Accession Number

P14921

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human Ets-1 around the phosphorylation site of S251

Clonality

Polyclonal

Tag

Protein C-ets-1

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-Ets-1 (S251) Polyclonal Antibody detects endogenous levels of Ets-1 protein only when phosphorylated at S251.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200