Isogarcinol
Isogarcinol (Cambogin) is a potent AChE and BChE inhibitor, with IC50 values of 1.13 and 8.30 μM, respectively. Isogarcinol also shows leishmanicidal activity, with an IC50 of 0.33 μM against L. donovani[1].
Product Specifications
CAS Number
71117-97-0
Product Name Alternative
Cambogin
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/isogarcinol.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@@]23C(OC(C)([C@H](C3)C/C=C(C)\C)C)=C(C([C@@]1(C(C)([C@@H](C2)C/C=C(C)\C)C)C/C=C(C)\C)=O)C(C4=CC(O)=C(C=C4)O)=O
Molecular Formula
C38H50O6
Molecular Weight
602.80
References & Citations
[1]Lenta BN, et al. Leishmanicidal and cholinesterase inhibiting activities of phenolic compounds from Allanblackia monticola and Symphonia globulifera. Molecules. 2007 Jul 20;12 (8) :1548-57.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE; BChE; Leishmania
Available Sizes
Frequently Asked Questions
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