Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

4E-BP1 (phospho Ser65) Polyclonal Antibody

Rabbit Anti-4E-BP1 (phospho Ser65) Polyclonal Antibody

Product Specifications

Background

EIF4EBP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Product Name Alternative

EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I

Gene ID

1978

Accession Number

Q13541

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human 4E-BP1 around the phosphorylation site of S64

Clonality

Polyclonal

Tag

Eukaryotic translation initiation factor 4E-binding protein 1

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

15kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-4E-BP1 (S64) Polyclonal Antibody detects endogenous levels of 4E-BP1 protein only when phosphorylated at S64.

Product Datasheet

https://www.abbkine.com/datasheet/ABP54079.pdf

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200

Other Product Names

EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q13541

CAS Number

9007-83-4

Isotype

Rabbit IgG

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Guinea pig lymphocyte-specific protein 1 (LSP1) ELISA Kit
MBS2613188-01 48 Well

Guinea pig lymphocyte-specific protein 1 (LSP1) ELISA Kit

Ask
View Details
Guinea pig lymphocyte-specific protein 1 (LSP1) ELISA Kit
MBS2613188-02 96 Well

Guinea pig lymphocyte-specific protein 1 (LSP1) ELISA Kit

Ask
View Details
Guinea pig lymphocyte-specific protein 1 (LSP1) ELISA Kit
MBS2613188-03 5x 96 Well

Guinea pig lymphocyte-specific protein 1 (LSP1) ELISA Kit

Ask
View Details
Guinea pig lymphocyte-specific protein 1 (LSP1) ELISA Kit
MBS2613188-04 10x 96 Well

Guinea pig lymphocyte-specific protein 1 (LSP1) ELISA Kit

Ask
View Details
Bcl-2 Monoclonal Antibody, APC Conjugated
bsm-10846M-APC 100 µL

Bcl-2 Monoclonal Antibody, APC Conjugated

Ask
View Details
Active PAI-1/tPA Complex (tPA/PAI1)
MBS2153614-01 0.01 mg

Active PAI-1/tPA Complex (tPA/PAI1)

Ask
View Details