CDHF10 Polyclonal Antibody

The cadherin EGF LAG seven-pass G-type receptor 2 encoded by CELSR2 is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.

CELSR2; CDHF10; EGFL2; KIAA0279; MEGF3; Cadherin EGF LAG seven-pass G-type receptor 2; Cadherin family member 10; Epidermal growth factor-like protein 2; EGF-like protein 2; Flamingo homolog 3; Multiple epidermal growth factor-like domains

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.

CELSR2; CDHF10; EGFL2; KIAA0279; MEGF3; Cadherin EGF LAG seven-pass G-type receptor 2; Cadherin family member 10; Epidermal growth factor-like protein 2; EGF-like protein 2; Flamingo homolog 3; Multiple epidermal growth factor-like domains