Dihydroartemisinin-d5
Dihydroartemisinin-d5 is deuterated labeled Dihydroartemisinin. Dihydroartemisinin is a potent anti-malaria agent.
Product Specifications
Product Name Alternative
Dihydroqinghaosu-d5; β-Dihydroartemisinin-d5; Artenimol-d5
UNSPSC
12352005
Target
Apoptosis; Autophagy; Isotope-Labeled Compounds; NF-κB; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Apoptosis; Autophagy; NF-κB; Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Solubility
10 mM in DMSO
Smiles
[2H][C@](O1)(O)[C@@](C([2H])([2H])[2H])([2H])C2CC[C@@H](C)C3CC[C@@]4(C)OO[C@]32[C@H]1O4
Molecular Formula
C15H19D5O5
Molecular Weight
289.38
References & Citations
[1]Hu W, et al. Dihydroartemisinin induces autophagy by suppressing NF-κB activation. Cancer Lett. 2014 Feb 28;343 (2) :239-48.|[2]Li HJ, et al. Dihydroartemisinin-praziquantel combinations and multiple doses of dihydroartemisinin in the treatment of Schistosoma japonicum in experimentally infected mice. Ann Trop Med Parasitol. 2011 Jun;105 (4) :329-33.|[3]Li YJ, et al. Dihydroartemisinin accentuates the anti-tumor effects of photodynamic therapy via inactivation of NF-κB in Eca109 and Ec9706 esophageal cancer cells. Cell Physiol Biochem. 2014;33 (5) :1527-36.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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