Desmin (phospho Ser60) Polyclonal Antibody

Rabbit Anti-Desmin (phospho Ser60) Polyclonal Antibody

Product Specifications

Background

DES encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

CAS Number

9007-83-4

Product Name Alternative

DES; Desmin

Gene ID

1674

Accession Number

P17661

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human Desmin around the phosphorylation site of S60

Clonality

Polyclonal

Tag

Desmin

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-Desmin (S60) Polyclonal Antibody detects endogenous levels of Desmin protein only when phosphorylated at S60.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200